Psychological and Social Impact of Recurrent Aphthous Ulcers among Young Adults
DOI:
https://doi.org/10.48165/IRJAY.2026.90205Keywords:
Chronic kidney disease, Vrikka Vikara, Panchkarma, Ayurveda, Renal functionAbstract
Chronic kidney disease (CKD) is a progressive and irreversible renal disorder associated with systemic complications and reduced quality of life. In Ayurveda, CKD can be correlated with Vṛikka Vikāra, arising due to imbalance of Tridoṣha (primarily Vāta and Kapha) leading to impaired Mutravaha Srotas function. Ayurvedic management focuses on Śodhana (detoxification) and Śamana (pacification) therapies along with ayurvedic formulations to improve renal function and alleviate symptoms. This holistic approach aims to enhance quality of life and slow disease progression. A 44-year-old male with a known case of CKD presented to Jeena Sikho Lifecare Limited Hospital, Lucknow, with complaints of fever (Jvara), generalized weakness (Daurbalya), gastric disturbances (Amlapitta), headache (Śiraśhūla), vomiting (Chhardi), throat infection (Kaṇṭhaśotha), shortness of breath (Śvāsa), disturbed sleep (Nidrānāśha), and generalized body ache (Aṅgamarda). The patient was managed with a comprehensive Ayurvedic treatment protocol including Ahāra–Vihāra Chikitsā (dietary and lifestyle modifications) and Panchkarma therapies. Following the intervention, complete resolution of fever, headache, vomiting, and generalized weakness was observed, with marked improvement in dyspnea, sleep quality, and body pain. Laboratory investigations showed a reduction in blood urea from 78.23 mg/dl to 68.8 mg/dl and improvement in glomerular filtration rate (GFR) from 12.11 ml/min to 24.08 ml/min. However, serum creatinine slightly increased from 3.22 mg/dl to 3.60 mg/dl, indicating persistent chronic renal impairment. Ayurvedic and Pañchkarma-based interventions demonstrated significant symptomatic relief and supportive improvement in renal function parameters in this CKD patient. These findings suggest that Ayurveda may serve as an adjunctive therapy in CKD management further controlled clinical studies are required to validate its efficacy.
Downloads
References
Hoekstra SP, Bishop NC, Faulkner SH, Bailey SJ, Leicht CA. Acute and chronic effects of hot water immersion on inflammation and metabolism in sedentary, overweight adults. J Appl Physiol (1985). 2018;125(6):2008-2018. doi:10.1152/japplphysiol.00338.2018.
Kovesdy CP. Epidemiology of chronic kidney disease: an update 2022. Kidney Int Suppl (2011). 2022;12(1):7-11. doi:10.1016/j.kisu.2021.11.003.
Chopra A, Doiphode VV. Ayurvedic medicine: core concept, therapeutic principles, and current relevance. Med Clin North Am. 2002;86(1):75-89. doi:10.1016/S0025-7125(03)00073-7.
Shlipak MG, Tummalapalli SL, Boulware LE, Grams ME, Ix JH, Jha V, et al. The case for early identification and intervention of chronic kidney disease: conclusions from a KDIGO controversies conference. Kidney Int. 2021;99(1):34-47. doi:10.1016/j.kint.2020.10.012.
Kumar S, Rampp T. Concept of fasting therapy in the traditional Indian medicine of Ayurveda. Curr Tradit Med. 2024;10(4):44-51. doi:10.2174/2215083809666230712111521.
Kovesdy CP, Davis JR, Duling I, Little DJ. Prevalence of anemia in adults with chronic kidney disease in a representative sample of the United States population: analysis of the 1999-2018 National Health and Nutrition Examination Survey. Clin Kidney J. 2023;16(2):303-311. doi:10.1093/ckj/sfac178.
Acharya M, Chaudhary G, Singh SP, Singh M, Richa. Clinical evaluation of chronic kidney disease management: integrating lifestyle modification and Ayurveda. Int J AYUSH. 2024;13(10):1152. doi:10.22159/prl.ijayush.v13i10.1152.
Kalantar-Zadeh K, Jafar TH, Nitsch D, Neuen BL, Perkovic V. Chronic kidney disease. Lancet. 2021;398(10302):786-802. doi:10.1016/S0140-6736(21)00519-5.
Verma P, Mahajan J, Kumar S, Acharya S. Lifestyle modification and nutrition: halt the progression to end-stage renal disease. Int J Nutr Pharmacol Neurol Dis. 2022;12(3):105-111. doi:10.4103/ijnpnd.ijnpnd_40_21.
Chen CH, Teitelbaum I. Physiology of peritoneal dialysis. In: Applied Peritoneal Dialysis: Improving Patient Outcomes. Singapore: Springer; 2021. p.11-23. doi:10.1007/978-981-15-9343-0_2.
Kulkarni SP. Parkinson’s disease from an Ayurveda perspective: opportunities and challenges for further research. In: Translational Models of Parkinson’s Disease and Related Movement Disorders. 2025. p.345-360. doi:10.1016/B978-0-443-14290-0.00019-3.
Purushothaman V, Santhanam R, Ravi P, Kuppusamy M. Development and validation of yoga program for patients with chronic kidney disease. Indian J Palliat Care. 2024;30(4):380-386. doi:10.25259/IJPC_112_2024.
Aggarwal A, Sokiya G, Sharma G. Management of chronic kidney disease-an Ayurveda case study. J Ayurveda Integr Med Sci. 2023;8(7):250-256. doi:10.21760/jaims.8.7.39.
Sharma P, Purohit S, Thakur D. Effect of Ayurvedic interventions with Pathya-apathya on clinical outcomes in patients with chronic kidney disease: a case series. J Ayurvedic Herb Med. 2025;11(3):83-88.
Agnivesa. Caraka Samhita. Sharma RK, Dash B, translators. Vol. 2. Reprint ed. Varanasi: Chowkhamba Sanskrit Series Office; 2010. Vimana Sthana, Chapter 5, Verse 20. p.179.
Gupta MC, Chand T. A critical review on commonly used herbal drugs in CKD. J Med Plants Stud. 2015;3(4):44-47.
Niharika, Parveen R, Parveen B, Umar S, Ahmad S. A comprehensive review on indigenous therapeutic approaches in kidney care using AYUSH medicine. Front Pharmacol. 2025;16:1588424. doi:10.3389/fphar.2025.1588424.
Neild GH. Life expectancy with chronic kidney disease: an educational review. Pediatr Nephrol. 2017;32(2):243-248. doi:10.1007/s00467-016-3388-8.
Sasane PU, Chandel A, Sahu SK, Nampalliwar A, Sinha CP, Namboothiri KP. Ayurvedic management of chronic kidney disease: classical texts, herbal interventions, and clinical evidence. Kidneys. 2026;15(1):54-64.
Anishetty S, Nellutla N, Suthari S, Shirisha M, Vasanthi AV. International Journal of Ayurveda and Pharma Research. Int J Ayur Pharma Res. 2025;13(8):53-79.
Bhumika HS, Pandareesh MD, Narasaraju T, Ramadas D. Bacopa monniera: a promising phytotherapeutic approach in management of diabetes-related complications. Phytother Res. 2026. doi:10.1002/ptr.9999.
Joshi N, Singh R, Sharma A, Dubey AK. Effect of Ayurvedic Basti therapy in the management of chronic kidney disease: a case report. J Ayurveda Integr Med. 2018;9(3):226-230. doi:10.1016/j.jaim.2017.07.005.
Hiremath V, Subramanya M, Patil V. A clinical study on gunjataila and tilataila shiroabhyanga in the management of Darunaka. Ayushdhara. 2016;3(4):792-796.
Pandey A, Azad AS, Bhardwaj A, Thakur G, Prakash G. Effectiveness of gravitational resistance and diet (GRAD) system in reversing chronic kidney disease among dialysis patients. Dayanand Ayurvedic College, Shridhar University.
Aiswarya CR, Anil Raj PK, Marikutty TC. Ayurvedic interventions in motor neuron disease. Int J Ayurveda Pharma Res. 2024;12(6):88-95.
Kolhe R, Acharya R. Analyzing the drug safety issue in Bhavaprakasha Nighantu-a critical review. Ayurpharm Int J Ayurveda Allied Sci. 2015;4:183-196.
Murali Krishna C, Gupta V, Bansal P, Kumar S, Sannd R, Narayana A. Review on plants mainly used for the preparation of Kshar Sutra. Int J Ayurvedic Med. 2010;1(1):12-22.
Kaundinya SD, Kaundinya DV. Meditation (Dhyan) versus relaxation: a review with comprehensive bibliography. Int J Basic Appl Physiol. 2013;2:240-257.
Bhujbal S, Malawade G. Therapeutic nutrition in Ayurveda for chronic kidney disease. In: Therapeutic Nutrition in Ayurveda. Boca Raton: CRC Press; p.283-298.
Rathi S, Rathi M. A clinical study of Yashtimadhu and Guduchi with special reference to Amlapitta. J Ayurveda Integr Med Sci. 2024;9(1):54-59. doi:10.21760/jaims.9.1.8.
Vaidya M, Upadhyay A, Kumar S, Sharma K. Exploration of therapeutic potential and evidence-based applications of Shwaskuthar Rasa: a scoping review. J Drug Res Ayurvedic Sci. 2024;9(2):75-85. doi:10.4103/JDRAS.JDRAS_102_23.
Dash B, Sharma BK. Charaka Samhita (Text with English Translation). Varanasi: Chowkhamba Sanskrit Series Office.
Brenner BM, Rector FC. The Kidney. 10th ed. Philadelphia: Saunders; 2015.
Sharma H, Clark C. Contemporary Ayurveda: Medicine and Research in Maharishi Ayurveda. Edinburgh: Churchill Livingstone; 2000.
Dushti MS. An in-depth study on Ayurvedic management of Vrikka Vikara (renal disorders) through Panchkarma Chikitsa with special emphasis on Mutravah Srotas Dushti. Blood Press. 2025;31(1):1-8.

