Madhumeha (T2dm) And Its Management Through Ayurveda: A Clinical Case Report
DOI:
https://doi.org/10.48165/IRJAY.2025.80612Keywords:
Ayurvedic management, Lifestyle modification, Madhumeha, Prameha, Type 2 Diabetes mellitus, YogaAbstract
The increasing prevalence of Type 2 Diabetes Mellitus (T2DM) in India, driven by lifestyle changes, urbanization, and genetic factors, necessitates comprehensive and holistic management approaches. This case study was conducted at Jeena Sikho Lifecare Limited, Ambala, India, and evaluates the effectiveness of Ayurvedic interventions in managing T2DM in a 34-year-old female patient. The patient presented with a known history of T2DM and complaints of shortness of breath. Following a thorough Ayurvedic evaluation, an individualized treatment protocol was initiated, comprising Ayurvedic formulations, dietary modifications, and lifestyle interventions. Over a three-month period, notable improvements were observed. The patient’s fasting blood sugar reduced from 307 mg/dl to 110 mg/dl, HbA1c decreased from 9.3% to 7.5%, and average glucose levels dropped from 232 mg/dl to 169 mg/dl. In addition to glycemic control, symptoms such as fatigue and shortness of breath were alleviated, indicating enhanced overall well-being and metabolic balance. These findings suggest that Ayurvedic intervention can be an effective complementary approach in the management of T2DM, contributing to both symptomatic relief and improved metabolic parameters. However, larger, controlled studies are warranted to confirm safety, efficacy, and long-term benefits, and to help establish standardized guidelines for the integration of Ayurvedic care in diabetes management.Downloads
References
Pradeepa R, Mohan V. Epidemiology of type 2 diabetes in India. Indian J Ophthalmol. 2021;69(11):2932–2938. https://doi.org/10.4103/ijo.IJO_1627_21
Pradeepa RG, Mohan V. Prevalence of type 2 diabetes and its complications in India and economic costs to the nation. Eur J Clin Nutr. 2017;71. https://doi.org/10.1038/ejcn.2017.40
Kalra S, Jena BN, Yeravdekar R. Emotional and psychological needs of people with diabetes. Indian J Endocrinol Metab. 2018;22(5):696–704. https://doi.org/10.4103/ijem.IJEM_579_17
Giri PA, Kausar HM. Assessment of risk of type 2 diabetes using Indian diabetes risk score: a community-based cross-sectional study in Marathwada region of Maharashtra. Indian J Community Health. 2024;36(3):329–334. https://doi.org/10.47203/IJCH.2024.v36i03.002
Shariq OA, McKenzie TJ. Obesity-related hypertension: pathophysiology, management, and the role of metabolic surgery. Gland Surg. 2020;9(1):80–93. https://doi.org/10.21037/gs.2019.12.03
Agency for Healthcare Research and Quality. 2021 National Healthcare Quality and Disparities Report. 2021. Available from: https://www.ncbi.nlm.nih.gov/books/NBK578537/
Tran KN, Phuong HN, Minh DD, Wens J. Health-related quality of life and associated factors among patients with type II diabetes mellitus in Hanoi, Vietnam. Health Psychol Open. 2021;8(1). https://doi.org/10.1177/2055102921996172
Hantoro IF, Syam AF, Mudjaddid E, et al. Factors associated with health-related quality of life in patients with functional dyspepsia. Health Qual Life Outcomes. 2018;16:83. https://doi.org/10.1186/s12955-018-0913-z
Richardson CR, Borgeson JR, Van Harrison R, et al. Management of Type 2 Diabetes Mellitus. Michigan Medicine, University of Michigan; 2021. Available from: https://www.ncbi.nlm.nih.gov/books/NBK579413/
Vyas OP, Rathor S. Madhumeha (type 2 diabetes mellitus) and its Ayurvedic management: a review. Int J Pharm Res Appl. 2024;9(3):2201–2206.
Madhavi A, et al. Review on etiopathogenesis and management of Madhumeha (diabetes mellitus). Int Ayurvedic Med J. 2017. Available from: http://www.iamj.in/posts/images/upload/3856_3862.pdf
Mangalge KS, Kaknurkar V. Ama as a causative entity of Medavaha Strotas disease Prameha. World J Pharm Res. 2020;9(15):1421–1426.
Yadav V, Meshram R, Sharma S, Shivhare S, Sharma V, Nagpal S. Ayurvedic review on Madhumeha w.s.r. diabetes mellitus. World J Pharm Res. 2024;13(3):411–418.
Gordon A, Buch Z, Baute V, Coeytaux R. Use of Ayurveda in the treatment of type 2 diabetes mellitus. Glob Adv Health Med. 2019;8:2164956119861094. https://doi.org/10.1177/2164956119861094
Agnivesha. Charaka Samhita of Agnivesha. Vol 1, Sutrasthana, Verses 78–80. Shukla V, Tripathi RD, editors. Vaidyamanorama Hindi commentary. Varanasi: Chaukhambha Sanskrit Pratishthan; 2014.
Katti P, Katti S, U R. Recent developments in integrated medicine approach in management of type 1 and type 2 diabetes mellitus: a review. J Ayurveda Integr Med Sci. 2025;9:143–152. https://doi.org/10.21760/jaims.9.11.20
Chattopadhyay K, Wang H, Kaur J, Nalbant G, Almaqhawi A, Kundakci B, et al. Effectiveness and safety of Ayurvedic medicines in type 2 diabetes mellitus: a systematic review and meta-analysis. Front Pharmacol. 2022;13:821810. https://doi.org/10.3389/fphar.2022.821810
Edavalath M. Ayurvedic dietary principles in prevention and management of diabetes: a review. Endocrinol Diabetes Obes. 2018;1. https://doi.org/10.31532/EndocrinolDiabetesObes.1.1.002
Woodyard C. Exploring the therapeutic effects of yoga and its ability to increase quality of life. Int J Yoga. 2011;4(2):49–54. https://doi.org/10.4103/0973-6131.85485
Sridharan K, Mohan R, Ramaratnam S, Panneerselvam D. Ayurvedic treatments for diabetes mellitus. Cochrane Database Syst Rev. 2011;(12):CD008288. https://doi.org/10.1002/14651858.CD008288.pub2
Dixit JV, Badgujar SY, Giri PA. Reduction in HbA1c through lifestyle modification in newly diagnosed type 2 diabetes mellitus. J Fam Med Prim Care. 2022;11(6):3312–3317. https://doi.org/10.4103/jfmpc.jfmpc_1677_21
Acharya MJ, Chaudhary G, Richa, Nilamwar SS. Reversion of uncontrolled type 2 diabetes mellitus with diabetic neuropathy by Ayurvedic intervention: a case study. Int J Adv Res. 2025;13(6):835–849.
Agnivesha. Charaka Samhita. Vol 1, Nidanasthana, Chapter 4, Verses 36–37. Shukla V, Tripathi RD, editors. Varanasi: Chaukhambha Sanskrit Sansthan; 2014.
Sushruta. Sushruta Samhita. Nidanasthana, Chapter 6, Verses 12–13. Dalhanacharya commentary. Varanasi: Chaukhambha Sanskrit Sansthan; 2014.
Agnivesha. Charaka Samhita. Vol 2, Chikitsasthana, Chapter 6, Verses 4–6. Shukla V, Tripathi RD, editors. Varanasi: Chaukhambha Sanskrit Sansthan; 2014.
Agnivesha. Charaka Samhita. Vol 2, Chikitsasthana, Chapter 6, Verses 44–46. Shukla V, Tripathi RD, editors. Varanasi: Chaukhambha Sanskrit Pratishthan; 2022.
Sushruta. Sushruta Samhita. Chikitsasthana, Chapter 11 (Prameha Chikitsitam), Verses 1–3. Dalhanacharya commentary. Varanasi: Chaukhambha Surbharati Prakashan.
Sushruta. Sushruta Samhita. Chikitsasthana, Chapter 11 (Prameha Chikitsitam), Verse 9. Dalhanacharya commentary. Varanasi: Chaukhambha Surbharati Prakashan.
Agnivesha. Charaka Samhita. Vol 1, Sutrasthana, Chapter 17, Verse 7. Shukla V, Tripathi RD, editors. Varanasi: Chaukhambha Sanskrit Pratishthan; 2022.
Peres M, Costa HS, Silva MA, Albuquerque TG. Health effects of low glycemic index and low glycemic load interventions in prediabetes and type 2 diabetes mellitus. Nutrients. 2023;15(24):5060. https://doi.org/10.3390/nu15245060
Panwar A, Kumar A, Pahwa P. Ayurvedic management of diabetic retinopathy: a case report. J Ayurveda Integr Med Sci. 2024;9(1):318–323. Available from: https://jaims.in/jaims/article/view/3045
Wadhwa R, et al. Management of complications of diabetes through Panchakarma. Int J Med Plants Nat Prod. 2018;4(4):1–4. https://doi.org/10.20431/2349-4859.04
Soni D, Kumar D. Madhumeha (diabetes mellitus) according to Ayurvedic classics: a brief review. Int Res J Ayurveda Yoga. 2021;4(11):Article 118. https://doi.org/10.47223/IRJAY.2021.4118
Katwal S, Shrivastava A, Sharma D. Prevention of Madhumeha and its complications through Ayurveda. Int J Ayurveda Pharma Res. 2017;5(2):63–66.
Thorup AC, Kristensen HL, Kidmose U, Lambert MNT, Christensen LP, Fretté X, et al. Bitter vegetables improve health status of type 2 diabetics: a randomized control trial. Nutrients. 2021;13(6):1813. https://doi.org/10.3390/nu13061813
Ali M, Ahmed S, Islam MR, Ahamed S, Rahaman M, Khatun M, Alam MA. Diabetes mellitus control including fruits in diet: a meta-analysis. J Diabetes Res. 2024;3:43–59.
Pitta S, Devi KP, Shailaja B. Diabetes mellitus (Madhumeha): an Ayurvedic review. Int J Pharm Pharm Sci. 2014;6(Suppl 2).
Sahu P, et al. Prevention and control of diabetes mellitus. Int J Appl Ayurved Res. 2017;3(3):487–498.
Raghuwanshi MS, Kumari S, Sharma K, Veena D, Sharma Y. Critical review on the concept of Madhumeha (diabetes mellitus). Int J Res Publ Rev. 2023;4(10):3229–3236.
Hawton K, Ferriday D, Rogers P, Toner P, Brooks J, Holly J, Biernacka K, Hamilton-Shield J, Hinton E.Slow down: Behavioural and physiological effects of reducing eating rate. Nutrients, 11(1), 50. https://doi.org/10.3390/ nu11010050
Sharma M, Vyas PP, Singhal HK. Role of Pathya-Apathya in the management of Prameha (Type-2 Diabetes Mellitus). Ayushdhara.2023;10(Suppl 2):38–43. Available from: https://ayushdhara.in/index.php/ayushdhara/article/view/1211
Sidar VK, Ratre GR, Bhagat P. Role of Pathya and Apathya in Madhumeha: A review. World J Pharm Med Res. 2023;9(1):48–52.
Lohar T, Kulkarni M. Role of Pathya-Apathya in the management of Prameha (Type-2 Diabetes Mellitus). J Ayurveda Integr Med Sci.2025;9(10):75–80. Available from: https://www.jaims.in/jaims/article/view/3933
Vyas P, Binawara BK, Narnolia PK. Effect of Gurmar (Gymnema sylvestre) leaf powder on glycemic control in type 2 diabetes mellitus. Int JPharm Clin Res. 2024;16(7):724–728.
Sharma S, Kumar R. Role of Karela in diabetes: A review. J Res Appl Sci Biotechnol. 2023;2:81–89. doi:10.55544/jrasb.2.1.10
Maji S. Role of neem leaves in diabetes and obesity. Unpublished manuscript; 2020.
Jagetia G. Role of Jamun (Syzygium cumini Skeels) in the treatment of diabetes: A review. Int J Complement Altern Med. 2018;11:Article ID 00374. doi:10.15406/ijcam.2018.11.00374
Kaur S, Singh S, Sabharwal S, Anand N, Khanna V, Baghel D. Overview on Giloy (Tinospora cordifolia) and Giloy Ghanvati with emphasis on hyperlipidemia, immunity, and diabetes. Asian Pac J Health Sci. 2021;8:69–74. doi:10.21276/apjhs.2021.8.4S.12
Gaddam A, Galla C, Thummisetti S, Marikanty RK, Palanisamy UD, Rao PV. Role of fenugreek in the prevention of type 2 diabetes mellitus in prediabetes. J Diabetes Metab Disord. 2015;14:74. doi:10.1186/s40200-015-0208-4
Majeed M, Narayanan N, Mundkur L, Prakasan P, Nagabhushanam K. Super fruit amla (Emblica officinalis Gaertn) in diabetes management and its complications: A concise review. Nutraceuticals. 2023;3:329–352. doi:10.3390/nutraceuticals3030026

